In diabetes mellitus, the patient’s body is unable to manufacture insulin or stops responding to the insulin produced by the pancreas. Without insulin, the circulating glucose molecules cannot cross the cellular membrane, resulting in elevated plasma but lowered intracellular glucose levels.
Long-term elevated glucose levels in the kidneys damage the capillaries that filter blood. This results in the movement of large molecules (such as protein) out of the blood stream and into the urine.Large protein molecules passing through the tubules in the nephron (filtering subunit of the kidney) create inflammation and scarring of the tubules with eventual loss of function.When enough nephrons are damaged, kidney failure will occur.
Dialysis is the process of cleaning and filtering the blood, ridding the body of harmful waste products and extra salts and fluids. It is used in people with kidney failure, including those with advanced diabetic nephropathy .
If you have diabetes, drinking alcohol will cause your blood sugar to rise. Plus, alcohol has a lot of calories. Alcohol stimulates your appetite, which can cause you to overeat and may affect your blood sugar control. Can interfere with the positive effects of oral diabetes medicines or insulin.
Pomegranate juice is known to be a good source of antioxidants.The patients who drank the pomegranate juice showed a reduction in both inflammation and damage caused by free radicals.