Blood contains a high concentration of circulating proteins. Normally, protein from the blood does not enter the urine. However, most people with stage 4 chronic renal disease spill protein in their urine, a condition known as proteinuria. The loss of protein in the urine may cause a total body protein deficiency. People with stage 4 chronic renal disease often have this complication. Low blood protein levels cause fluid to leak from the blood into the tissues. Thus, people with severe renal disease often have swelling (edema) in their extremities, especially the feet, ankles and lower legs.
How to treat proteinuria with stage 4 kidney failure?
Lower your salt intake.
Control your blood sugar levels.
Lower your blood pressure. Proteinuria is often found in combination with high blood pressure, because high blood pressure weakens capillaries in the kidneys.
Reduce the amount of protein you eat. Remember that protein comes from many different foods, not just meat and fish.